BACKGROUND:The number of total knee arthroplasty has exceeded that of total hip arthroplasty, however, there are fewer cases receiving total knee arthroplasty in China. This discrepancy can be explained by the uncertain attitude of patients towards the efficacy of total knee arthroplasty. More studies are needed to explore the clinical efficacy and related influencing factors. n OBJECTIVE:To investigate the changes of knee function and its influencing factors after total knee arthroplasty in aged patients with osteoarthritis. n METHODS:60 patients with osteoarthritis were treated with total knee arthroplasty surgery and rehabilitation training in Anshan Central Hospital from August 2012 to May 2014. The patient’s age, weight, height, body mass index, muscle strength, VAS score, HSS score, ROM before and after total knee arthroplasty surgery, as wel as early postoperative application of CPM were recorded. The correlation between postoperative HSS score and other factors was analyzed with Pearson correlation method. n RESULTS AND CONCLUSION:The postoperative HSS score and ROM [87.3±5.5, (98.4±7.9)°] were significantly higher than those before surgery [45.8±5.7, (66.5±4.3)°,P < 0.05]. The postoperative HSS score was negatively correlated with preoperative VAS scores, preoperative HSS scores, preoperative ROM, and early postoperative application of CPM (P < 0.05). Total knee arthroplasty has an important treatment value of aged patients with osteoarthritis and can significantly improve joint function of patients. At the same time preoperative knee pain score, preoperative HSS score, preoperative ROM and early postoperative CPM application wil influence the treatment effect.%背景：近年来国外报道的全膝关节置换的数量已经快速增加超过全髋关节置换的手术量，然而国内行全膝关节置换的患者却远比行人工全髋关节置换患者少，具体原因可能为患者对于全膝关节置换的疗效持不确定的态度。对于其具体疗效以及相关影响因素，还需要更多的研究给予确认。n 目的：对经过全膝关节置换治疗老年骨关节炎患者的关节功能以及其影响因素进行探讨。n 方法：选择鞍山市中心医院2012年8月至2014年5月收治的骨关节炎患者60例，对患者进行全膝关节置换治疗以及康复训练，同时通过跟踪随访，统计记录患者年龄、体质量、身高、体质量指数、肌力、置换前后膝关节目测类比评分、膝关节特种外科医院评分、膝关节屈曲活动度评分以及术后早期CPM应用情况，了解疗效，并采用 Pearson相关分析法分析置换后膝关节特种外科医院评分与其他因素的关系。n 结果与结论：通过全膝关节置换后的膝关节特种外科医院评分和膝关节活动度分别为87.3±5.5，(98.4±7.9)°，治疗前的膝关节特种外科医院评分和膝关节活动度分别为45.8±5.7，(66.5±4.3)°，置换后较置换前显著改善，差异有显著性意义(P<0.05)。置换后膝关节特种外科医院评分与置换前膝关节疼痛目测类比评分、置换前膝关节特种外科医院评分、置换前膝关节活动度、置换后早期CPM应用呈负相关关系(P<0.05)。提示全膝关节置换对骨关节炎患者具有重要的修复价值，能显著改善患者的关节功能，置换前膝关节疼痛评分、置换前膝关节特种外科医院评分、置换前膝关节活动度以及置换后早期CPM应用会影响其修复效果。
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