Objective To investigate the therapeutic effectiveness and safety of ultrasound-guided high intensity focused ultrasound (USgHIFU) ablation for uterine fibroids in patients with retroposition of uterus. Methods 45 fibroids in 32 patients with anteposition of uterus and 37 fibroids in 24 patients with retroposition of uterus were treated with USgHIFU. MRI was used to assess treatment response. Adverse effects were recorded. Results MRI showed the average fractional ablation was (88. 7 + 7. 0)% in patients with anteposition of uterus,(84. 8 + 13. 8)% in patients with retroposition of uterus. During HIFU procedure, more patients with retroposition of the uterus complained sacral pain than those with anteposition of the uterus (95. 8% vs 50. 0%). Conclusions USgHIFU is safe and effective in ablating uterine fibroids in patients with retroposition of uterus.%目的 研究实时超声监控的超声消融治疗后位子宫子宫肌瘤的有效性及安全性.方法 前位子宫32例45个肌瘤；后位子宫24例37个肌瘤.治疗前及治疗后第2天行增强MRI检查；分析治疗中、治疗后患者所有副反应.结果 术后增强MRI显示前位、后位子宫组肌瘤平均消融率分别为(88.7±7.0)％和(84.8±13.8)％.后位子宫组骶尾部疼痛发生率明显高于前位子宫组(95.8％ vs 50.0％).结论 超声引导的高强度聚焦超声能安全、有效地治疗后位子宫肌瘤.
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