Objective To compare mid-grade pulmonary hypertension (PH) patients with normal adults about variations of curvature radius of interventricular septum (IVS) during a cardiac cycle by speckle tracking imaging. Methods Short-axis images among the basal and middle levels were recorded in 23 patients with mid-grade PH and 20 control subjects. Radius curvature (RC) and RC ratio (RCR) of IVS and left ventricular lateral-posterior wall (LV-LPW) were measured and calculated by speckle tracking imaging. Results There was statistical difference between changes of the basal and middle levels of RCIVS and RCLVLPW in patients with mid-grade PH and there was also statistical difference between changes of the basal and middle levels of RCIVS between mid-grade PH group and control group,as well as the levels of RCR. Conclusions The pressure change between left ventricle(LV) and right ventricle (RV) in patients with PH can be evaluated by observing the variations of RCIVS.%目的 应用斑点追踪技术研究比较中度肺动脉高压(PH)患者与正常成人在整个心动周期中室间隔曲率半径RC的变化.方法 选择23例中度PH患者(PH组)和20例健康志愿者(对照组),二维超声心动图采集左室短轴基底段、中间段图像,利用斑点追踪技术测量并计算全心动周期室间隔和侧后壁的RC及曲率半径比值(RCR).结果 整个心动周期中,PH组各节段室间隔RC与相应节段侧后壁RC及对照组相应节段室间隔RC相比较,均明显增大,差异有统计学意义(P均＜0.01);PH组基底段与中间段RCR与对照组相应节段RCR相比较,均增大,差异有统计学意义(P均＜0.05).结论 通过观察全心动周期室间隔RC的变化可以评价PH时左右心室之间的压力变化.
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