目的 探讨二维应变成像(two-dimensional strain,2DS)和组织多普勒成像(tissue Doppler imaging,TDI)测得应变及应变率定量评价无左室重构高血压患者右室心肌长轴收缩功能的应用价值.方法 无左室重构的高血压患者50例(高血压组),正常人60例(Xq照组),分别应用2DS与TDI测得右室游离壁基底段、中段及心尖段长轴收缩峰值速度(V)、收缩峰值应变(S)、收缩峰值应变率(SR).结果 (1)与对照组比较,2DS显示HT组各节段S、SR值均减低,差异均有统计学意义(P均<0.05);TDI显示HT组中段S、SR值减低,差异均具有统计学意义(P<0.05),基底段及心尖段S、SR值两组间差异无统计学意义(P均>0.05);2种检测方式显示HT组各节段V值差异均无统计学意义(P>0.05).(2)2组内各节段V、中段S及中段SR的2种方法测值相关性良好(κ=0.522～0.880,P均<0.05).结论 无左室重构的高血压患者右室长轴收缩功能已受影响,2DS和TDI均可评价右室长轴收缩功能,其中2DS可更准确、敏感地评价右室长轴收缩功能.%Objective To discuss the application value of strain and strain rate measured by 2-dimensional strain (2DS) and tissue Doppler imaging(TDI)in patients with hypertension(HT) and non left ventricular remodeling and normal controls.Methods Longitudinal peak systolic velocity(V) ,peak systolic strain(S) ,peak systolic strain rate(SR)of right ventricular free wall were recorded for basal,mid and apical segment measured by 2DS and TDI respectively in 50 patients with hypertension and non left ventricular remodeling and 60 healthy controls.Results ( 1 ) Compared with the controls, 2DS manifested S and SR of all segments in patients with HT were with significant deviation(P＜0.05).TDI displayed S and SR of mid segment in patients with HT were having significant deviation(P＜0.05).V of all segments in patients with HT measured by 2DS and TDI were not significantly different(P＞0.05).(2)In each group, V of all segments,S and SR of mid segment measured by 2DS and TDI had positive correlations(r=0.522～0.880, P＜0.05 for ail).Conclusions Right ventricular longitudinal systolic function in patients with hypertension and non left remodeling has been damaged.Both 2DS and TDI can evaluate right ventricular longitudinal systolic function, in addition, 2DS can assess more exactly and sensitively.
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