Objective To investigate the influence of subclinical hypothyroidism ( SCH ) on complications and pregnancy outcomes . Methods A retrospective chart review was performed on 1 053 pregnant women with SCH ( SCH group ) and 3 899 pregnant women with normal thyroid function ( control group ) diagnosed by serum thyroid function screening .The following parameters of two groups were compared:serum levels of TSH, FT4 and TPOAb, maternal complications and pregnancy outcomes .Results Serum TSH level of SCH group was higher than control group (t=39.001,P<0.01) and TPOAb positive rate was higher in SCH group (χ2 =40.753,P<0.01). The incidences of premature delivery and neonatal asphyxia were higher in SCH group (χ2 =8.638,P<0.05;χ2 =22.209,P<0.01).The incidence of neonatal low birth weight was higher in SCH group , but the difference showed no statistical significance (χ2 =2.323,P>0.05).Conclusion SCH is common in pregnant women .It maybe contribute to adverse pregnancy outcomes such as abortion and premature.More attention should be paid on SCH screening in pregnant women .%目的：研究亚临床甲状腺功能减退（ SCH）对孕期并发症及妊娠结局的影响。方法选取经甲状腺功能筛查诊断为SCH的孕妇1053例（ SCH组），正常孕妇3899例（对照组），比较各组TSH、FT4、TPOAb，孕期并发症及妊娠结局情况。结果SCH组的TSH水平及TPOAb阳性率均高于对照组（t＝39．001，P＜0．01；χ2＝40．753，P＜0．01）。 SCH组的早产率及新生儿窒息率高于对照组（χ2＝8．638，P＜0．05；χ2＝22．209，P＜0．01），SCH组新生儿低出生体重率高于对照组，但无统计学意义（χ2＝2．323，P＞0．05）。结论 SCH是孕期常见病，可能与流产、早产等妊娠不良结局的发生相关，应重视妊娠妇女的SCH筛查。
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