首页> 中文期刊> 《中国妇幼健康研究》 >早期微量喂养影响低出生体重儿营养及免疫

早期微量喂养影响低出生体重儿营养及免疫

         

摘要

目的 探讨早期微量喂养对低出生体重儿营养状况及免疫功能的影响.方法 选择低出生体重儿为研究对象,根据喂养方法分成早期微量喂养组和常规喂养组,比较两组患儿喂养前后营养状况(血清前白蛋白、白蛋白、总蛋白和转铁蛋白)和免疫功能(IgG、IgA、IgM、CD3+、CD4+和CD8+)的差异.结果 早期微量喂养组和常规喂养组患儿喂养前的前白蛋白、白蛋白、总蛋白、转铁蛋白、IgG、IgA、IgM、CD3+、CD4+和CD8+无明显差异(均P>0.05);喂养后两组患儿前白蛋白、白蛋白、总蛋白、转铁蛋白、IgA、IgM、CD3+、CD4+和CD8+显著增高(均P<0.05),Ig G显著降低(t=2.682,P<0.05);早期微量喂养组患儿喂养后的前白蛋白、白蛋白、总蛋白、转铁蛋白、IgG、IgA、IgM、CD3+、CD4+和CD8+显著高于常规喂养组(t值分别为4.287、6.251、5.784、2.665、2.682、5.346、2.870、4.332、3.399和2.402,均P<0.05).结论 早期微量喂养可显著改善低出生体重儿的营养状况,提高免疫功能.%Objective To study the effects of early minimal feeding ( EMF ) on low birth weight infants' nutritional status and immune function. Methods Low birth weight infants were divided into EMF group and common feeding group ( CON group ) according to feeding style. The nutritional status ( PA, ALB, TP and TRF ) and immune function ( IgG, IgA, IgM, CD3 + , CD4 + and CD8 ) of two groups were compared. Results The differences in pre-feeding PA, ALB, TP, TRF, IgG, IgA, IgM, CD3 + , CD4+ and CD8+ between EMF group and CON group were not significant ( all P > 0.05 ). After feeding the levels of PA, ALB, TP, TRF, IgA, IgM, CD3 + , CD4 + and CD8 + of two groups increased significantly ( all P <0. 05 ) and the level of IgG declined remarkably ( t = 2. 682 ,P <0. 05 ). The levels of PA, ALB, TP, TRF, IgG, IgA, IgM, CD3 + , CD4 + and CD8 + in EMF group were significantly higher than those in CON group ( t value was 4.287, 6.251, 5.784, 2.665, 2.682, 5.346, 2.870,4.332, 3.399 and 2.402, respectively, all P<0.05). Conclusion EMF can improve the nutritional status and strengthen immune function of low birth weight infants.

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