The causes of arbitrary combination therapy for malignant tumors are analyzed, and the concept and working mode of individualized combination therapy are put forward. Furthermore, the shaping conditions of the individualized combination therapy are expatiated upon in the following aspects: innovation management mode, implementation of clinical guidelines, technical regulations development, standard construction of the discipline, specialist training in oncology, unified popular science education. A client-oriented human-machine conversation expert system for single disease is developed and utilized, which overcomes the influence of various personal factors on clinical decision-making, helps to translate the . Advantage technology into clinical benefits for patients truly, and promotes and ensures clinical implementation of the individualized combination therapy.[Chinese Medical Equipment Journal,2011,32(10):96-98]%通过分析当前“随意性联合治疗”的原因,提出恶性肿瘤“个体化联合治疗”的概念和工作模式,并从“创新管理模式、落实临床指南、制定技术规范、学科标准建设、专科医师培养、统一科普宣教”等6个方面阐述其形成条件.面向服务对象的单病种人机对话专家系统的研制和应用,有助于克服临床决策中各种人为因素的干扰,有利于将优势技术真正转化为患者的临床获益,促进和保障恶性肿瘤“个体化联合治疗”的临床实践.
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