目的 探究运动医学科住院患者抑郁对免疫的影响,并提出护理策略.方法 根据医院性焦虑和抑郁量表(HADS),将患者分为抑郁组和非抑郁组,用流式细胞仪测量他们的免疫指标.比较两组患者的免疫指标.运用Spearman相关分析探索抑郁与免疫的关系,运用多元线性回归分析抑郁对免疫的影响.结果 120例患者中有83例表现为抑郁情绪(69.17％).抑郁组患者的NK细胞比例和B细胞比例显著低于非抑郁组(P<0.001).患者的抑郁分数与NK和B细胞的比例显著负相关(P<0.001).在均衡人口学和疾病情况后,抑郁分数显著影响NK和B细胞的比例(P<0.001).结论 患者的抑郁情绪是免疫的影响因素,护士应关注患者的心理状况,给予患者人文护理.%Objective:To investigate the influence of depressive mood of inpatients in sports medicine depart-ment on immunity and put forward nursing strategy. Methods:According to Hospital Anxiety and Depression Scale ( HADS) , the patients were divided into the depression group and non depression group, and their immune indexes were measured by flow cytometry. The immune indexes of patients between two groups were compared; Spearman correlation analysis was used to explore the relationship between depressive and immunity, and Multiple Linear Re-gression was used to analyze the effect of depressive on immunity. Results:In the 120 patients, there were 83 pa-tients showed depressive mood (69. 17％). The proportion of the NK cell and B cell in depression group was signif-icantly lower than that in the non depression group (P<0. 001). The patients' depression score was significantly negatively correlated with the proportion of NK cell and B cell ( P<0 . 001 ) . After adjusting for the socio-demo-graphic factors and disease status, depression score significantly influenced the proportion of NK cell and B cell ( P<0. 001). Conclusions:Patients' depressive mood is an influencing factor of their immunity. Nurses should pay attention to the patients' psychological condition and give them humanistic care.
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