Objective Endoscopic repair of acute perforations of the gastrointestinal tract would reduce the requirement of surgical repair.We analyzed the safety and efficacy of Over-the-Scope-Clip endoscopic closure of acute perforations of the gastrointestinal tract.Methods We analyzed 18 patients in Hospitals of Mcigill Medical School with acute iatrogenic perforations which included 2esophageal,3 gastric,5 duodenal,and 8 colonic perforations.GI doctors used the Over-the-Scope-Clip to repair these perforations and determined that perforated points were successful closure and there are no adverse events.Results 15 patients' perforations weré closed successfully.The success rate is 84％.The mean endoscopic closure time was 4-5 minutes.Three patients' perforations were not closed,and then the three patients were treated by surgeries.Conclusion The Over-the-Scope-Clip Endoscopic closure of acute iatrogenic perforations is successful and effective.%目的 对消化道急性穿孔内镜下Over-The-Scope-Clip system(OTSC)金属夹闭合术的疗效进行评估.方法 对18例急性医源性消化道穿孔的患者进行了回顾性,多中心的临床评估.其中有2例食道穿孔,3例胃穿孔,5例十二指肠穿孔,和8例结肠穿孔.对这18例患者,内镜医生均使用了OTSC金属夹系统,一种新型的合金耙状夹,对穿孔部位进行了闭合术治疗.结果 18例患者中,15例穿孔被及时成功地内镜下闭合,成功率为84％;3例患者未闭合成功,随之进行了外科手术.平均内镜下闭合术所需时间为4～5 min.结论 急性医源性消化道穿孔内镜下OTSC夹闭合术是成功有效的.
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