Objective To study the relationship of left ventricular hypertrophy (LVH) and heart rate variability (HRV), ventricular arrhythmias in patients with essential hypertension (EH). Methods 108 EH patients in our hospital were divided into LVH group (52 cases) and non-LVH group (control group, 56 cases) in accordance with whether complicating LVH. The 24 h ECG situations and HRV time domain indices were monitored by dynamic ECG Analyzer, the relationship between LVH and HRV, ventricular arrhythmias was analyzed. Results The LVPW, LA and IVS in LVH group were thicker than those in control group, the LVEF was lower than that in control group (P<0.05). The levels of ventricular premature contraction (VPC) in LVH group were higher than those in control group (P<0.05). The HRV in two groups had no statistical difference (P>0.05). IVS, LVDd and age were the independent risk factors of VPC level. Conclusions The incidence of ventricular arrhythmias in EH patients with LVH increases significantly, but the HRV is not correlated with LVH.%目的：研究原发性高血压患者左心室肥厚与心率变异性及室性心律失常之间的关系。方法选择我院收治的原发性高血压患者108例，并根据患者是否存在左心室肥厚分为左心室肥厚组（52例， LVH组）和无左心室肥厚组（56例，对照组）。采用动态心电图分析仪监测患者24 h心电图情况以及其心率变异性的时域指标，分析左心室肥厚与心率变异性及室性心律失常的相关性。结果 LVH组LVPW、 LA、 IVS均显著厚于对照组， LVEF显著低于对照组（P<0.05）。 LVH组室性期前收缩级别比对照组高（P<0.05）。两组患者的心率变异性比较无显著差异（P>0.05）。 IVS、 LVDd和年龄均为室性期前收缩级别的独立危险因素。结论室性心律失常发生率在原发性高血压合并左心室肥厚患者中有所增加，但患者的心率变异性与左心室肥厚却无相关性。
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