首页> 中文期刊> 《临床医学研究与实践》 >益气活血法对冠心病多重危险因素及稳定型心绞痛患者内皮功能影响的临床探讨

益气活血法对冠心病多重危险因素及稳定型心绞痛患者内皮功能影响的临床探讨

         

摘要

目的:探讨益气活血法对冠心病多重危险因素及稳定型心绞痛患者内皮功能的影响。方法按照随机分组法将我院收治的80例冠心病患者均分为试验组和对照组,两组患者给予常规冠心病二级预防西医综合治疗,对照组在此基础上加用血府逐瘀胶囊治疗,试验组在此基础上加用脑心通胶囊治疗,比较两组患者治疗前后血糖血脂常规、PAgT、FDM变化情况以及中医证候疗效。结果试验组患者治疗显效率和总有效率均明显高于对照组( P<0.05);两组患者治疗后 FMD均明显升高( P<0.05);两组治疗前后hs-CRP均无明显变化( P>0.05);治疗后,对照组患者 PAgT明显高于试验组( P<0.05);试验组治疗前后PAgT无明显变化( P>0.05);两组治疗前、后FPG、TC、TG、HDL-C、LDL-C水平无明显差异( P>0.05)。结论益气活血法治疗冠心病中医证候疗效显著,能够明显改善患者FMD功能,改善冠心病多重危险因素,具有较高临床应用价值。%Objective To observe the effect of supplementing Qi and activating blood circulation therapy on risk factors and endothelial function influence in patients with stable angina pectoris (SAP). Methods Eighty cases of patients with SAP were randomly divided into two groups. All of them were treated by the secondary prevention of coronary heart disease. On this basis, the control group received Xuefu Zhuyu Capsule, and the study group received Naoxintong capsule. The levels of blood glucose, blood lipid, PAgT and FDM, and efficacy between the two groups were compared. Results The significant efficiency rate and total effective rate of the study group were much better than those of the control group (P0.05);after the treatment, the PAgT level in the control group was significantly higher than that in the study group (P0.05);there was no statistically significant difference in FPG, TC, TG, HDL-C and LDL-C between the two groups before and after the treatment (P>0.05). Conclusion Supplementing Qi and activating blood circulation therapy can improve the SAP of patients with TCM syndrome, improve the function of patients with FMD, improve the multiple risk factors for CHD, and it has high clinical value.

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