Therapeutic Outcome of Botulinum Toxin Type A for Patients with Low Bladder Compliance Secondary to Spinal Cord Injury

H. Chen; M. P. Huang; T. H. Huang; C. H. Jiang; J. W. Zeng; L. L. Zhou; Q. L. Liu; Q. Q. Li; X. Y. Yang

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Therapeutic Outcome of Botulinum Toxin Type A for Patients with Low Bladder Compliance Secondary to Spinal Cord Injury

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Objective: To evaluate the efficacy and safety of botulinum toxin type A (BTX-A) in treating patients with low bladder compliance (BC) secondary to spinal cord injury (SCI). Methods: From 2011 to 2016, we retrospected patients who received BTX-A injections for LBC secondary to SCI. The primary outcomes were urodynamic parameters including maximum detrusor pressure (Pdetmax), bladder compliance (BC). Related adverse events were recorded. Results: 72 SCI patients were selected (62 males, 10 females, age range 18 - 52 years;mean age 28.5 years). 12 weeks after BTX-A injection, Pdetmax decreased from 51.02 cmH2O to 28.31 cmH2O. BC increased from 3.64 ml/cmH2O to 10.08 ml/cmH2O. 12 patients had mild transient haematuria for 1 - 2 days. Conclusion: Intradetrusor BTX-A injection was effective and safe for patients with low BC secondary to SCI.

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来源
《泌尿学期刊（英文）》 |2017年第11期|207-211|共5页
作者
H. Chen; M. P. Huang; T. H. Huang; C. H. Jiang; J. W. Zeng; L. L. Zhou; Q. L. Liu; Q. Q. Li; X. Y. Yang;
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作者单位

Department of Urology;

Guangdong Provincial Work Injury Rehabilitation Hospital and Jinan University;

Guangdong;

China;

Departments of Urology;

Qingyan City People’s Hospital;

Jinan University;

Guangdong;

China;

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原文格式 PDF
正文语种 chi
中图分类肿瘤学;
关键词
Botulinum; Toxin; Type; A; Low; Bladder; Compliance; Spinal; Cord; Injury;

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Therapeutic Outcome of Botulinum Toxin Type A for Patients with Low Bladder Compliance Secondary to Spinal Cord Injury

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