目的：探讨酚妥拉明持续泵注治疗小儿肺炎的疗效及对血液动力学的影响。方法：选取我科2015年5月～2016年3月收治的符合重症肺炎诊断标准的住院患儿120例，将其随机分为治疗组和对照组各60例，两组患儿均采用相同的综合治疗，包括吸氧、抗感染、抗病毒、营养支持治疗，治疗组在上述治疗的基础上加用酚妥拉明1μg/( kg.min)微量泵24h缓慢静脉注入，连用3～5日，观察和对比分析各组的疗效；同时比较两组的治疗效果和用药后于用药后5min、15min、30min、60min、24h收缩压（SBP）、舒张压（DBP）及心率等。结果：治疗组显效65%，有效30%，总有效率95%，与对照组相比，治疗组显效、总有效率明显升高( P<0.05)；与对照组相比，治疗组在用药后于用药后5min、15min、30min、60min、24h收缩压（SBP）、舒张压（DBP）及心率均无显著性差异。结论：酚妥拉微量泵缓慢静脉注入治疗婴儿重症肺炎疗效明显，并没有引起治疗组的血液动力学发生变化，可见采取酚妥拉明持续泵注辅助治疗婴儿重症肺炎值得在临床推广运用。%Objective:To investigate the effect of phentolamine infusion in the treatment of infantile pneumonia and hemodynamic effect. Methods:in our hospital from May 2015 to March 2016 were accorded with the diagnostic criteria of severe pneumonia in 120 cases of patients, which were randomly divided into treatment group and control group of 60 cases, two patients were treated with comprehensive treatment the same, including oxygen, anti infection, nutritional support treatment, the treatment group was treated with phentolamine and 1 g/on the basis of the above treatment (kg.min) micro pump 24h slow intravenous injection, for 3~5 days, and to observe the curative effect of each group were analyzed at the same time than the contraction;compare the therapeutic effect of two groups after treatment and after treatment 5min, 15min, 30min, 60min, 24h (SBP), diastolic blood pressure (DBP) and heart rate. Results:the treatment group was 65%, effective 30%, the total efifciency of 95%, compared with the control group, treatment group, the total efifciency was signiifcantly increased (P<0.05);compared with the control group, the treatment group after treatment in contraction after treatment 5min, 15min, 30min, 60min, 24h (SBP), Shu Zhang Ya (DBP) there were no signiifcant differences in heart rate and. Conclusion:phento pull micro pump efifcacy in the treatment of infants with severe pneumonia signiifcantly slow intravenous injection, the treatment group did not cause hemodynamic changes, visible by phentolamine infusion in adjuvant treatment of infants with severe pneumonia in clinical application.
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