OBJECTIVE: To investigate the application status of antibiotics and causes of irrational drug application in outpatient of Qingdao the Fifth People ' s Hospital ( hereinafter referred to as "our hospital") , so as to promote the rational drug application in clinic .METHODS:12789 prescriptions from Jul .2015 to Dec.2016 were randomly extracted in our hospital .Statistical analysis was conducted on the general data and types of antibiotics , drug combination and irrational types of prescriptions .RESULTS:898 cases( accounting for 7.02％ of the total number of spot checks) were antibiotics prescriptions , the average consumption sum of per prescription was 174.27 yuan, the categories of drugs were 2.99 and the application rate of national essential drugs was 53.84％; there was no overstepped application of antibiotics . The most common used antibiotics in outpatient of our hospital were fluoroquinolone , followed by β-lactam and nitroimidazole . There were 699 cases ( 77.84％) of single-drug prescriptions , 195 cases ( 21.71％) of combined-drug prescriptions and 4 cases ( 0.45％) of three-drug prescriptions .Prescriptions with irrational drug application were 90 prescriptions ( 10.02％) .The irrational types mainly performed as irrational dosing frequency , without indications , improper administration dosage , nonstandard writing of prescriptions , irrational drug combination and contraindication , etc.CONCLUSIONS: The application of antibiotics in outpatient of our hospital is basically rational , yet there are still some problems .It is necessary to further strengthen the management on antibiotics , strengthen the training and learning , improve the cooperation between clinicians and pharmacists , so as to promote the rational drug use in clinic .%目的:了解青岛市第五人民医院(以下简称"我院")门诊抗菌药物应用现状及不合理用药的原因,促进临床合理用药.方法:随机抽取我院2015年7月—2016年12月处方12789张,对其中抗菌药物处方的一般情况、抗菌药物类别、联合用药及不合理处方类型进行分析.结果:抗菌药物处方898张(占抽查总处方数的7.02％),处方平均金额为174.27元,处方平均用药品种数为2.99种,国家基本药物使用率为53.84％,无医师越级使用抗菌药物情况.我院门诊应用的抗菌药物以氟喹诺酮类最为常见,其次为β-内酰胺类和硝基咪唑类.单一用药处方699张(占77.84％),二联用药处方195张(占21.71％),三联用药处方4张(占0.45％).不合理用药处方90张(占10.02％),主要包括给药频次不合理、无指征用药、给药剂量不合理、处方书写不规范、联合用药不合理和存在用药禁忌证等.结论:我院门诊抗菌药物使用基本合理,但仍存在一定问题,应进一步加强对抗菌药物的管理,加强培训和学习,并加强医药合作,促进临床合理用药.
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