目的：探讨注射用重组人干扰素α-2b（假单胞菌）雾化吸入佐治疱疹性咽峡炎的疗效。方法：选取疱疹性咽峡炎患儿290例作为研究对象，以随机数字表法分为观察组135例和对照组155例。观察组患者给予利巴韦林静脉滴注，并联合注射用重组人干扰素α-2b（假单胞菌）雾化吸入，对照组给予利巴韦林静脉滴注，观察2组患儿的疗效、退热及疱疹消失时间。结果：观察组患者的退热及疱疹消失时间均少于对照组，病程明显缩短，差异有统计学意义（ P＜0.05）；观察组患者的总有效率为96.30％（130／135），对照组为76.13％（118／155），2组的差异有统计学意义（P＜0.05）；2组患儿均未出现不良反应。结论：注射用重组人干扰素α-2b（假单胞菌）联合利巴韦林治疗疱疹性咽峡炎，可缩短病程，安全有效。%OBJECTIVE:To probe into the efficacy of injection of recombinant human interferon α-2b( P.putida) in inhalation treatment of blister measles angina.METHODS:290 children with blister measles angina were selected to be divided into observation group (135cases) and control group (155 cases) via the random number table.The observation group were treated with intravenous drip of ribavirin combined with recombinant human interferonα-2b( P. putida) in inhalation treatment, while the control group only received intravenous drip of ribavirin.The efficacy, disappearance time of fever and herpes in two groups were observed.RESULTS:The disappearance time of fever and herpes in observation group were shorter than that of control group, the treatment course was shortened, with statistical significance(P<0.05).The total effective rate of observation group was 96.30%(130/135), and control group was 76.13%(118/155), with statistical significance(P<0.05).There was no adverse drug reactions in both groups. CONCLUSIONS:The efficacy of injection of recombinant human interferonα-2b( P.putida) in inhalation treatment of blister measles angina is safe and effective,.
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