目的：了解北京石景山医院（以下简称“我院”）门诊镇静催眠药的使用情况，为临床合理用药提供参考。方法：提取我院2014年1—6月门诊镇静催眠药处方共8713张，对患者资料与镇静催眠药使用情况进行回顾性调查分析。结果：我院门诊镇静催眠药的使用人群以＞40岁的中老年患者为主，且女性多于男性；镇静催眠药使用率最高的科室为神经内科；使用频率最高的药品为佐匹克隆；新型镇静催眠药的用药频度及限定日费用均高于苯二氮�类药；佐匹克隆、阿普唑仑、硝西泮等3药的药物利用指数＞1；佐匹克隆、氯硝西冸、阿普唑仑、苯巴比妥等4药的销售金额排序／DDDs排序（排序比）接近于1，表明其销售金额与用药人次的同步性好。结论：我院门诊镇静催眠药使用基本合理，但存在药物依赖性问题，需进一步加强应用管理。%OBJECTIVE:To investigate the utilization of sedative hypnotics for outpatients in Beijing Shijingshan Hospital ( hereinafter referred to as “our hospital”) , and to provide reference for rational drug use in clinic . METHODS:8 713 outpatient prescriptions of sedative hypnotics from Jan .to Jun.2014 were selected , retrospective analysis was conducted on the general information of patients and the utilization of sedative hypnotics .RESULTS:the majority patients with sedative hypnotics were the middle and elderly patients who were older than 40 years old, and more women than men .The most use of sedative hypnotics department was neurology department , and the most frequently used drugs was zopiclone .The DDDs and DDDc of the new type of sedative hypnotics were higher than that of benzodiazepine .DUI of zopiclone, alprazolam, nitrazepam was over 1.The consumption sum ranking/DDDs ranking ( ranking ratio ) of zopiclone, nitrazepam, alprazolam, phenobarbitone closed to 1, which showed good synchronization between consumption sum and person-time of drug use .CONCLUSIONS: The utilization of sedative hypnotics for outpatients in our hospital was basically rational , but there are still some problems with drug addiction which needs the further strength of application management .
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