OBJECTIVE:To probe into the efficacy of self-made prescription in treatment of kidney calculi of deficiency-excessiveness types .METHODS:90 cases with kidney calculi of deficiency-excessiveness types admitted into the Community Health Services Center of Guangzhou Yuexiu District Beijing St .from Jun.2013 to Nov.2014 were selected as the research objects , who were divided into observation group and control group via the random number table , with 45 cases in each group .The control group were treated with orally hydrochlorothiazide ( 25 mg/time, 3 times/day), and orally anisodamine (10 mg/time, 3 times/day), and patients with urinary tract infection would be treated with antibiotics .The observation group received the self-made prescription treatment .The efficacy of patients, efficacy of TCM syndrome and indicators changes of urine β2-MG, blood β2-MG, Cr and BUN before and after treatment in two group of patients were observed .RESULTS: The total effective rate of observation group was significantly higher than that of the control group [ 93.33%( 42/45 ) VS 82.22%( 37/42 ) ] , with statistically significant difference(P<0.05).The urineβ2-MG, bloodβ2-MG, Cr and BUN of observation group was significantly lower than that of before treatment ,and it was lower than the control group , with statistically significant difference ( P<0.05).Also, the total effective rate of TCM syndrome in observation group was significantly higher than that in the control group [ 91.11%(41/45)VS 80.00%(36/45)], the difference was significant(P<0.05).CONCLUSIONS:Self-made prescription in treatment of kidney calculi of deficiency-excessiveness types has good efficacy , which is worthy of clinical promotion .%目的：探讨自拟方治疗虚实夹杂型肾结石的疗效。方法：选取2013年6月—2014年11月广州市越秀区北京街社区卫生服务中心收治的90例虚实夹杂型肾结石患者为研究对象，按随机数字表法分为观察组和对照组各45例。对照组患者应用双氢克尿塞口服、1次25 mg、1日3次；山莨菪碱口服、1次10 mg、1日3次，尿路感染患者，应用抗菌药物治疗。观察组患者应用自拟方加减进行治疗，观察2组患者的疗效、中医证候疗效以及治疗前、后的尿β2-微球蛋白（β2-MG），血β2-微球蛋白（β2-MG），血肌酐（Cr），血尿素氮（BUN）指标的变化情况。结果：观察组患者的总有效率为93.33％（42／45），明显高于对照组的82.22％（37／42），差异有统计学意义（ P＜0.05）。观察组患者的尿β2-MG、血β2-MG、Cr、BUN均明显低于治疗前，且明显低于对照组，差异有统计学意义（P＜0.05）。观察组患者的中医证候疗效总有效率为91.11％（41／45），明显高于对照组的80.00％（36／45），2组的差异有统计学意义（ P＜0.05）。结论：自拟方治疗虚实夹杂型肾结石疗效较好，值得临床推广。
展开▼
