目的：探讨银川市妇幼保健院儿科住院患者抗菌药物使用的合理性。方法：采用回顾性横断面调查方法，选择该院2012年8月26日至9月25日（干预前）和2013年1月26日至2月25日（干预后）的全部住院患者病历，对其抗菌药物的应用情况进行比较分析。结果：干预后该院儿科患者的抗菌药物使用率由干预前的70.98％下降至62.68％，抗菌药物使用强度由干预前的37.02 DDDs/（100人·d）下降至20.16 DDDs/（100人·d），抗菌药物费用由干预前的7.02万元下降至6.16万元，抗菌药物用药不合理使用率由34.59％下降至15.72％。结论：采取有效、可行的干预措施，可明显降低抗菌药物的使用率，缩短平均住院时间，使抗菌药物的合理应用明显提高，儿科患者抗菌药物平均使用经费明显下降，对社会、医院和患者均有益。%OBJECTIVE:To evaluate the antibiotic use in pediatric inpatients in Yinchuan Women & Children’s Health Care Hospital and evaluate the impact of rational use of drugs. METHODS:By a retrospective cross-sectional survey,all the medical re-cords in this hospital from Aug. 26 to Sept. 25 in 2012(before intervention)versus from Jan. 26 to Feb. 25 in 2013(after interven-tion)were collected for analysis of the antibiotic use. RESULTS:After intervention,the rate of patients with antibiotic use declined from 70.98% to 62.68%;the antibiotic use density declined from 37.02 DDDs/(100 persons·d)to 20.16 DDDs/(100 persons·d);the costs of antibiotics declined from 70 200 yuan to 61 600 yuan and the rate of irrational antibiotic use declined from 34.59% to 15.72%. CONCLUSIONS:The effective and feasible intervention measures greatly reduced the rate of patients with antibiotic use, the average hospital stay and the pediatric mean cost of antibiotics yet significantly improved the rate of rational antibiotic use, which are of great benefits for society,hospitals and patients.
展开▼
