With seed and peels dregs of hippophae as material, polysaccharide was dissolved fully by breaking the cytoderm. Four methods with enzymatic, cold solvent, microwave and ultrasonic were compared to the amount of assessment indicators for Polysaccharide dissolved. The results showed that the best method in breaking the cytoderm was microwave treatment and the best conditions was:power 600 W;5 min/time broken;two times;interval 3 min, Under this condition, crude polysaccharide extraction rate of seed and peels dregs of hippophae was 1.892%.%以沙棘榨汁提油后的籽及果渣为原料，经过破壁手段而使多糖充分溶出。本试验采用生物酶法、冻溶、微波及超声波四种方法进行对比破壁，以粗多糖提取率为考核指标，确定了最佳细胞破壁方法为微波破碎，并且确定微波破碎工艺条件为：功率600 W，破碎5 min/次，破碎次数为2次，间歇3 min，在此条件下沙棘籽及果皮渣中粗多糖提取率为1.892%。
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