Fermenter size, number and agitator type were discussed what advantages were to optimize the fermenter under same annual production capacity. Compared proposed 70 m3fermenters with existing 40 m3fermenter, it indicated when fermenter was scaled up to 70 m3, required fermenter per day can be greatly reduced from 6 to 3.4. and i.e. batch frequency can be extended to 7.0 hours from 4.0 hours. This will create a significant decline of the batch shift and cleaning load will be dramatically reduced accordingly every day. Meanwhile the more important is that batch capacity was increased to1.75 times, from original 4200 kg/Bath to 7350 kg/Bath (active solid). Limiting fermenter numbers was helpful to control the cost of fermenters. Compared with the impellor agitator used in existing 40m3 fermenters, power consumption of combined-impeller agitator varied little with the amount of volatile ventilation, good gas dispersion ability and high dissolved oxygen levels.%本文讨论了在同样年生产能力下,发酵罐尺寸、数量和搅拌器选型的最优化方案设计.研究结果表明:与已有的40 m3发酵罐相比,采用放大的70 m3发酵罐,每批需要的发酵罐数量从6个显著减少到3.4个,即降低了发酵罐转换频率,则发酵罐转料和清洗等的操作负荷也将大幅度降低;更重要的是每批的产量从4200 kg(活性固体)/批增加到7350 kg(活性固体)/批,达到1.75倍;同时合理控制发酵罐数量以降低设备投资成本;采用涡轮式和轴流式结合的组合式叶轮搅拌器,通气和搅拌效果提高,而且耗电量较低.
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