设计合成一个柔性插入配体dcpip(dcpip=2-(2,3-环己烯基咪唑并[4,5-f]邻菲略啉)及其钌(Ⅱ)多吡啶配合物[Ru(bpy)2(dcpip)](ClO4)2(bpy=2,2'-联吡啶)和[Ru(phen)2(dcpip)](ClO4):(phen=1,10-邻菲咯啉).采用元素分析和质谱对其进行表征.用电子吸收光谱、荧光光谱和粘度测试研究配合物与DNA作用.研究结果表明,配合物与DNA之间通过插入作用结合.%A new ligand dcpip and its ruthenium(Ⅱ) complexes [Ru(bpy)2 (dcpip)]2+ (bpy = 2,2'-bipyridine) and [Ru(phen)2(dcpip)]2+ (phen = 1,10-phenanthroline, dcpip = 2-(2,3-cyclohexenyl)imidazo[4,5-f][1,10]phenanthroline)were synthesized and characterized by elemental analysis and mass spectra. The DNA-binding properties of these complexes were investigated by spectroscopic methods and viscosity measurement. The experimental results indicated that the two complexes interact with calf thymus DNA (CT-DNA) by intercalative mode.
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