Objective To observe Carboprost tromethamine practical effect of preventing postpartum hemorrhage, postpartum hemorrhage explore its value in high-risk mothers.Methods December 2012 - November 2013 100 cases of postpartum hemorrhage presence of maternal risk factors, according to a random number table will be divided into the experimental group, 50 cases in the control group 50 cases, the fetus is applied immediately after oxytocin treatment control group maternal, application Carboprost tromethamine treatment experimental group mothers were compared clinical outcomes.Results Compared with the control group, the experimental group at high risk of maternal postpartum hemorrhage treatment better. Experimental group postpartum incidence of postpartum hemorrhage, postpartum hemorrhage average, the duration of postpartum lochia postpartum anemia incidence and complication rate was 6%,(368.41±101.22)mL,(17.32±5.01)d, 6%, 24.0%, more than the control group were observed indicators, the statistical signiifcance of differences between the two groups(P<0.05).Conclusion Carboprost tromethamine was better prevention of postpartum hemorrhage, postpartum hemorrhage is worthy of further applications in high-risk women, the promotion.%目的：观察卡前列素氨丁三醇预防产后出血的实际效果，探讨其在产后出血高危产妇中的应用价值。方法收集2012年12月至2013年11月100例存在产后出血倾向的产妇，按随机数字表法将其分成实验组50例，对照组50例，胎儿娩出后立即应用催产素治疗对照组产妇，应用卡前列素氨丁三醇治疗实验组产妇，比较两组临床治疗效果。结果与对照组相比，实验组产后出血高危产妇的治疗效果更佳，实验组产后出血发生率、平均产后出血量、产后恶露持续时间、产后贫血发生率及并发症发生率分别为6%、（368.41±101.22）mL、（17.32±5.01）d、6%、24.0%，以上观察指标均优于对照组，两组差异存在统计意义（P＜0.05）。结论卡前列素氨丁三醇预防产后出血的效果较佳，值得在产后出血高危产妇中进一步应用、推广。
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