Objective To explore the correlation between the concentration of serum HBsAg,HCCR and AFP. Methods Serum samples of 400 cases patients with HBsAg and 100 cases healthy people were collected. According to the concentration of HBsAg, the serum samples were assigned into four groups. Enzyme-linked immuno sorbent assay was used to detect HCCR and HBsAg. Chemoluminescence was used to detect AFP. Results When HCCR and AFP in the groups of different concentration of serum HBsAg were compared with those in the control group, their levels were different significantly (P<0.05). The levels of serum HCCR and AFP increased gradually with the increase of the concentration of HBsAg and the level of HCCR was positively correlated with the level of AFP (P<0.01). Conclusions The levels of serum HCCR and AFP increased gradually with the increase of the concentration of HBsAg and the level of HCCR was positively correlated with the level of AFP.%目的：探讨血清乙型肝炎病毒表面抗原浓度与人宫颈癌基因蛋白及甲胎蛋白的相关性。方法收集100例健康体检者和400例HBsAg 阳性患者的血清，根据 HBsAg 浓度分为 A、B、C、D 四组。采用 ELISA 检测 HCCR 和 HBsAg，化学发光法检测 AFP。结果不同 HBsAg 浓度组与对照组 HCCR、AFP 比较，差异均有统计学意义（P<0.05）；HBsAg 浓度越高，血清中 HCCR、AFP 水平越高，且HCCR 与 AFP 成正相关。结论随着 HBsAg 浓度的升高，血清中 HCCR 与 AFP 水平逐渐增高，且 HCCR 与 AFP 成正相关。
展开▼
