Objective To investigate the correlation between changes in Tei index, NT-pro brain natriuretic eptide (NT-proBNP) and cardiac function classification in patients with acute myocardial infarction after percutaneous coronary intervention (PCI). Methods Seventy patients with acute myocardial infarction were enrolled in this study. The difference of NT-proBNP and Tei index were compared in patients of different cardiac function after PCI. The relationship was analyzed. Results There was statistically significant difference in Tei index, NT-proBNP and LVEF between the patients of different cardiac function after PCI (P＜0.05＝. Tei index and NT-proBNP increased as the heart dysfunction aggravated, while LVEF decreased as the heart dysfunction aggravated. Correlation analysis showed a significant positive correlation between Tei index and NT-proBNP, but a significant negative correlation between Tei index, NT-proBNP and LVEF. Conclusion Tei index and NT-proBNP can sensitively reflect the cardiac function of patients with acute myocardial infarction after PCI. The combined application of Tei index and NT-proBNP would be more objective and accurate.%目的 研究急性心肌梗死患者行PCI介入治疗后,不同心功能状态患者的NT-proBNP,Tei指数的变化,及其与心功能分级的关系.方法 选取在我科治疗的70例急性心肌梗死患者作为研究对象,比较介入治疗后不同心功能分级的患者Tei指数及血浆NT-proBNP的差异,并分析其相关性.结果 不同心功能分级患者的Tei指数、NT-ProBNP以及LVEF差异均有统计学意义(P＜0.05),提示Tei指数与NT-ProBNP随心功能分级增加而升高；LVEF则随心功能分级增加而降低.线性相关性分析发现,Tei指数与NT-proBNP呈正相关(P＜0.05)；Tei指数、NT-proBNP均与LVEF呈负相关(P＜0.05).结论 Tei指数与NT-proBNP可较为敏感的反映PCI治疗急性心肌梗死后心功能的恢复情况,两者联合应用更为客观和准确.
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