Objective To understand the clinical effect of reactive lactobacillus pharmacy combined with clotrimazole in curing vulvovaginal candidiasis during pregnancy.Method 127 patients with the disease were randomly divided into an experimental group and a control group.The experimental group were given reactive lactobacillus pharmacy combined with clotrimazole,while the control group were given clotrimazole only.The clinical effects of the medicines on the two groups one week after treatment and recurrence rate within one month and two months were recorded and analyzed.Findings One week after treatment,the total clinical efficacy of the designated medicine on the experimental group was 95.38%.The efficacy of clotrimazole on the control group was 93.55%.The difference was not statistically significance(P>0.05).One month and two months after treatment,the recurrence rates of the experimental group were 2.17%and 6.52%respectively, while the recurrence rates of the control group were 15.38% and 25.64% respectively.The differences between the two groups in recurrence rate were statistically significant (P<0.05).Conclusion The clinical effect of reactive lactobacillus pharmacy combined with clotrimazole in curing vulvovaginal candidiasis during pregnancy was found to bear no prominent difference than that of the clotrimazole.However, it has great advantage in preventing the recurrence of the disease.%目的：探讨克霉唑联合乳酸杆菌活性制剂治疗妊娠期外阴阴道假丝酵母菌病（ vulvovaginal candidiasis ，VVC）的临床疗效。方法将127例妊娠期VVC患者随机分成观察组和对照组，观察组采用克霉唑联合乳酸杆菌活性制剂治疗，对照组单用克霉唑治疗，观察治疗结束后1周的临床疗效和1个月、2个月的复发率。结果治疗结束后1周，观察组的总有效率为95．38％，对照组为93．55％，差异无统计学意义（ P＞0．05）。观察组1个月、2个月复发率分别为2．17％、6．52％；对照组分别为15．38％、25．64％，两组差异有统计学意义（ P＜0.05）。结论克霉唑联合乳酸杆菌活性制剂治疗妊娠期VVC效果与单用克霉唑无明显差异，但在预防复发方面占明显优势。
展开▼
