•Anti-vascular endothelial growth factor ( anti-VEGF ) drugs are widely used in the ophthalmology. The main indications are wet age-related macular degeneration ( wAMD) . By searching the related literature, we draw a lot of anti-VEGF drugs’ rare application case reports and clinical research progress in Ophthalmic diseases except wAMD. There are still gaps between vitro and the clinical use of those researches. The prospect of the application of anti- VEGF drugs is hopeful and attractive. More researches is needed.%抗血管内皮生长因子( anti-VEGF )药物在眼科应用广泛，主要适应证为湿性年龄相关性黄斑变性( wAMD )通 过检索国内外相关文献，我们得出很多抗VEGF药物在眼科实验室及临床其他疾病的应用个案报道及研究进展，部分为超适应证应用研究，为我们拓展了思维，但到临床应用阶段仍有差距。抗VEGF药物应用前景广阔，需更多研究以进一步发掘和明确。
展开▼
