老年黄斑变性( age-related macular degeneration,AMD)是西方国家白种人不可逆性视力下降的首要原因。目前, AMD的治疗方法主要有抗血管内皮生长因子抗体( Anti-vascular endothelial growth factor,Anti-VEGF)的药物治疗、光动力学疗法( photodynamic therapy,PDT)、局部应用曲安奈德(triamcinolone acetonide,TA)及激光治疗(纳秒激光等)等。本文通过对比分析老年黄斑变性的不同治疗方法的作用原理、治疗效果、副作用、经济成本,为临床治疗提供依据。%Age - related macular degeneration ( AMD ) is the leading cause of irreversible visual loss in elderly people among white - dominated population. At percent, treatment for AMD includes anti - vascular endothelial growth factor antibody ( Anti- VEGF ) drug treatment, photodynamic therapy ( PDT ) , topical application of triamcinolone acetonide ( TA ) and laser therapy ( nanosecond laser) etc. Through comparative analysis of different treatment methods of AMD, we review the mechanism, clinical efficacy, adverse events and cost effectiveness to provide the basis for clinical treatment.
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