目的：分析功能性泪溢患者泪道泵功能及泪液蛋白成分与正常泪液的异同。n 方法：功能性泪溢患者100例200眼,正常对照20例40眼。观察指标包括 Schirmer I试验、按压泪囊部时Schirmer I试验、泪膜破裂时间,同时采用ELISA测定功能性泪溢患者泪液主要蛋白含量,并与正常人的泪液对比。n 结果：正常受试者按压泪囊部时与开放泪囊部时的Schirmer I测试值比较,差异有显著意义( t=-4.008, P0.05)。功能性泪溢患者泪膜破裂时间缩短( t=-5.382, P0.05)。n 结论：泪道泵功能破坏在功能性泪溢中存在重要影响,功能性溢泪患者泪液蛋白质发生变化。%AIM: To study the lacrimial pump functions and tear proteins of patients with functional Epiphora. n METHODS: One hundred cases ( 200 eyes ) with functional epiphora and 20 cases ( 40 eyes ) of nonfunctional controls were recruited and under routine ophthalmic examinations, including Schirmer I test, Schirmer I test while pressing the lacrimal sac, tear film break-up time ( BUT ) . Enzyme linked immunosorbent assay ( ELISA) was used to detect main tear proteins, and the results were compared with control group. n RESULTS:Compared the result of the Schirmer I test on the normal subjects while pressing the lacrimal sac with that of releasing the lacrimal sac, the difference was significant (t=-4. 008, P0. 05). The mean BUT was significantly shorter than that in the normal subjects ( t=-5. 382, P0. 05). n CONCLUSION: The damage of lacrimal pump function plays a great role in the functional epiphora and the tear proteins of functional epiphora patients changed.
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