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首页> 中文期刊> 《国际口腔科学杂志》 >Effects of water-aging for 6 months on the durability of a novel antimicrobial and protein-repellent dental bonding agent

Effects of water-aging for 6 months on the durability of a novel antimicrobial and protein-repellent dental bonding agent

         
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摘要

cqvip:Biofilms at the tooth-restoration bonded interface can produce acids and cause recurrent caries. Recurrent caries is a primary reason for restoration failures. The objectives of this study were to synthesize a novel bioactive dental bonding agent containing dimethylaminohexadecyl methacrylate(DMAHDM) and 2-methacryloyloxyethyl phosphorylcholine(MPC) to inhibit biofilm formation at the tooth-restoration margin and to investigate the effects of water-aging for 6 months on the dentin bond strength and protein-repellent and antibacterial durability. A protein-repellent agent(MPC) and antibacterial agent(DMAHDM) were added to a Scotchbond multi-purpose(SBMP) primer and adhesive. Specimens were stored in water at 37 °C for 1, 30, 90, or 180 days(d).At the end of each time period, the dentin bond strength and protein-repellent and antibacterial properties were evaluated. Protein attachment onto resin specimens was measured by the micro-bicinchoninic acid approach. A dental plaque microcosm biofilm model was used to test the biofilm response. The SBMP + MPC + DMAHDM group showed no decline in dentin bond strength after water-aging for 6 months, which was significantly higher than that of the control(P 0.1). In conclusion, a bonding agent with MPC and DMAHDM achieved a durable dentin bond strength and long-term resistance to proteins and oral bacteria. The novel dental bonding agent is promising for applications in preventive and restorative dentistry to reduce biofilm formation at the tooth-restoration margin.

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  • 来源
    《国际口腔科学杂志》 |2018年第3期|P.160-167|共8页
  • 作者

    Ning Zhang; Ke Zhang; Michael D.Weir; David J.Xu; Mark A.Reynolds; Yuxing Bai; Hockin H.K.Xu;

  • 作者单位

    Department of Orthodontics School of Stomatology Capital Medical University Beijing China;

    Biomatexrials&Tissue Engineering Division Department of Endodontics Periodontics and Prosthodontics University of Maryland Dental School Baltimore MD USA;

    Center for Stem Cell Biology&Regenerative Medicine University of Maryland School of Medicine Baltimore MD USA;

    Marlene and Stewart Greenebaum Cancer Center University of Maryland School of Medicine Baltimore MD USA;

    Department of Mechanical Engineering University of Maryland Baltimore County MD USA;

  • 原文格式 PDF
  • 正文语种 chi
  • 中图分类 口腔科学;
  • 关键词

    DMAHDM; SBMP+MPC+DMAHDM;

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