首页> 中文期刊> 《国际病理科学与临床杂志》 >树突状纤维黏液脂肪瘤6例临床病理分析并文献复习

树突状纤维黏液脂肪瘤6例临床病理分析并文献复习

         

摘要

目的:探讨树突状纤维黏液脂肪瘤(dendritic fibromyxolipoma,DFML)的临床病理特征.方法:收集6例DFML,分析其临床病理特征及免疫表型,并复习相关文献.结果:男4例,女2例,年龄27~73(平均50)岁;4例发生于肩、腰背部、大腿的体表,1例位于髂窝,1例位于肠系膜处.肿块均边界清楚或包膜完整.所有病例镜下特征相似,均由纤细的梭形细胞或星芒状细胞,混杂多少不等的成熟脂肪细胞组成,背景为黏液样间质及绳索或瘢痕样胶原纤维.6例病例梭形细胞和星状细胞vimentin,CD34弥漫强(+),3例Bcl-2(+),3例灶性(+);其中1例S-100灶性(+).结论:DFML是一种罕见的良性脂肪瘤,需与多种黏液样肿瘤鉴别,肿块需完整切除.%Objective: To investigate the clinicopathological characteristics of dendritic fibromyxolipoma (DFML). Methods: The clinicopathological and immunophenotypic features in 6 cases of DFML were analyzed. The literatures were reviewed. Results: Four male patients and two female patients aged 27-73 years (mean, 50 years). Four cases occurred in the subcutis of the shoulder, waist and back, thighs, one case is located in the iliac fossa, one case occurred in mesentery. They were well circumscribed or encapsulated. Microscopically, the tumor mainly consisted of small spindle and stellate cells, admixture of mature adipose tissue, with abundant myxoid stroma and rope-like or slender collagen fibers. Immunohistochemically, the spindle and stellate cells show positive for CD34 and vimentin, a half of all cases expressed Bcl-2, others locally expressed Bcl-2. In particular, one case locally expressed S-100. Conclusion: DFML is a rare benign soft tissue tumor, which needs to be differentiated from a variety of other myxoid tumors. The tumor needs to completely removed.

著录项

  • 来源
    《国际病理科学与临床杂志》 |2017年第3期|527-531|共5页
  • 作者单位

    南通大学附属苏州市吴江区第一人民医院病理科,江苏 苏州 215200;

    第三军医大学大坪医院野战外科研究所病理科,重庆 400042;

    第三军医大学大坪医院野战外科研究所病理科,重庆 400042;

    南通大学附属苏州市吴江区第一人民医院病理科,江苏 苏州 215200;

    南通大学附属苏州市吴江区第一人民医院病理科,江苏 苏州 215200;

    南通大学附属苏州市吴江区第一人民医院病理科,江苏 苏州 215200;

  • 原文格式 PDF
  • 正文语种 chi
  • 中图分类
  • 关键词

    树突状纤维黏液脂肪瘤; 鉴别诊断; 临床病理特征;

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