牙根吸收是正畸治疗过程中一种常见的并发症，影响正畸牙牙根吸收的因素十分复杂。牙根吸收的过程与骨吸收过程相似，由与破骨细胞形态相似功能相仿的破牙骨质细胞发挥主要作用。破骨细胞蛋白酪氨酸磷酸酶（PTP-oc）主要在破骨细胞中表达，且对破骨细胞具有正调节作用。本文探讨PTP-oc的作用机制，旨在为防治牙根吸收提供一定的参考依据。%Root resorption is a common complication of orthodontic treatment whose factors are very complicated. The processe of root resorption is similar to bone resorption. The cementoclast plays a main role in this process, and it is similar to the shape and function of osteoclasts. Osteoclastic protein-tyrosine phosphatase(PTP-oc) is mainly expressed in osteoclasts, and has a positive regulatory effect on osteoclasts. In this paper, the mechanism of PTP-oc is discussed, which provides a reference for the prevention and treatment of root resorption.
展开▼
