氧化石墨烯是石墨烯经含氧官能团化学修饰得到的复合材料,除兼有石墨烯优良的物理、化学性质外,还可提供较大的表面积,促进干细胞增殖、成骨分化,且具有独特的生物相容性和抗菌性能,从而为其在生物医学方面的应用提供了广泛的前景.本文综述了氧化石墨烯应用于药物与蛋白传递、骨组织再生、抗菌抗炎方面的研究进展及其可能存在的不良反应.%Graphene oxide(GO) is a chemically modified composite material of graphene by oxygen-containing functional groups.In addition to excellent chemical and physical properties of graphene,GO can provide larger surface area,promote stem cell proliferation,osteogenic differentiation,and has unique biocompatibility and antibacterial properties,resulting in broad prospects of application in the field of biomedicine.This article reviews the progress of graphene oxide on drug and protein delivery,bone tissue engineering,anti-inflammatory and antibacterial actions,and the possible toxic and side effects.
展开▼
