目的 探究不同时机注射欣母沛预防产后出血的临床价值.方法 选取105例接受分娩而且可能有出血倾向的产妇,根据患者注射药物的不同,将所有患者分为对照组和观察组,再根据注射欣母沛的时间不同,将观察组又分为早期组和晚期组.对照组仅给予缩宫素20 U进行常规治疗;早期组在胎儿分娩后立即静脉滴注20 U缩宫素和注射欣母沛治疗;晚期组则先使用20 U缩宫素后,当产妇出血量＞ 300ml时,再注射欣母沛.比较分析三组产后出血情况以及各项监测指标.结果 观察组中早期组出血量[(289.2±24.3) ml]明显低于晚期组[(435.3±31.9) ml] (P＜0.05);早期组分娩后24 h血红蛋白水平[(10.23±1.02) g/dL]低于晚期组[(11.62±1.06) g/dL] (P＜0.05);观察组中早期组第三产程时间[(7.73±2.16) min]也明显短于晚期组[(9.13±2.56) min] (P＜0.05).结论 在胎儿娩出后尽早注射欣母沛预防和降低产后出血有着显著的效果,值得临床广泛应用.%Objective To explore the clinical value of injecting hemabate at different times for preventing postpartum hemorrhage.Methods One hundred and five pregnant women who were in parturition and might have bleeding tendency were selected.The patients were divided into a control group and an observation group according to different injection times.The control group were routinely treated with 20 U oxytocin;the early group were intravenously dripped 20 U oxytocin and took hemabate immediately after delivery;the late group were intravenously dripped 20 U oxytocin immediately after delivery and took hemabate when the bleeding volume was over 300 ml.The postpartum hemorrhage and the monitoring indicators were compared and analyzed.Results The bleeding volume and the level of hemoglobin 24 h after delivery were lower and the third stage of labor was shorter in the early group than in the late group [(289.2 ± 24.3) ml vs.(435.3 ± 31.9) ml,(10.23 ± 1.02) g/dL vs.(11.62 ± 1.06) g/dL,and (7.73 ± 2.16) min vs.(9.13 ± 2.56) min] in the observation group (P ＜ 0.05).Conclusions Using hemabate immediately after delivery for the prevention of postpartum hemorrhage is quite effective,so it is worth being clinically applied.
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