Objective To compare the efficacy of minimally invasive percutaneous nephrolithotomy holmium laser lithotripsy and open renal lithotomy in the treatment of complex renal calculi.Methods 130 cases of complex renal calculi were randomly divided into control group and observation group,65 cases in each group.Patients in control group were given open renal lithotomy,while patients in observation group were given minimally invasive percutaneous nephrolithotomy holmium laser lithotripsy.Perioperative indicators,stone clearance rate and postoperative complications of two groups were compared.Results Perioperative indicators (blood loss,operative time,leaving bed time,hospital stay) in observation group were significantly lower than those in control group (P＜0.05).The stone clearance rate of observation group was 96.92％,which was significantly higher than 72.31％ of control group (P＜0.05).The rate of postoperative complications of observation group was 6.15％,which was significantly lower than 32.31％ of control group (P＜0.05).Conclusion Compared with open renal lithotomy,minimally invasive percutaneous nephrolithotomy holmium laser lithotripsy can effectively cure complex renal calculi,with advantages of less bleeding,shorter operative time,leaving bed time and hospital stay,higher stones clear rate,and lower postoperative complications rate.%目的 比较复杂性肾结石临床微创经皮肾镜钬激光碎石术和开放性肾切开取石术的治疗效果.方法 选取130例复杂性肾结石患者,随机分为对照组和观察组,每组各65例.对照组患者采用开放性肾切开取石术,观察组患者则采用微创经皮肾镜钬激光碎石术.观察两组围手术期指标、结石清除率及术后并发症情况.结果 观察组围手术期指标(术中出血量、手术时间、下床活动时间、住院时间)均明显低于对照组(P＜0.05).观察组结石清除率为96.92％,明显高于对照组的72.31％ (P＜0.05).观察组术后并发症率为6.15％,明显低于对照组的32.31％(P＜0.05).结论 与开放性肾切开取石术相比,经皮肾镜钬激光碎石术治疗复杂性肾结石临床效果显著,且具有出血量少、手术时间短、下床活动时间早、住院时间短、结石清除高及术后并发症率低的优点.
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