目的 分析我院门诊注射中心药品不良反应( ADR)发生的特点与一般规律,为临床合理、安全用药提供参考.方法 对医院2011年门诊注射中心发生的104例药品ADR进行统计分析.结果 19 ～ 40岁患者发生ADR比例最大(63例,占60.58％)；104例药品ADR中,静脉滴注较其它给药途经更易引起ADR(101例,占97.12％)；抗微生物药物引起的ADR最多(70例,占67.31％),氟喹诺酮类是引发ADR的主要抗微生物药(28例,占40.00％)；中药注药剂ADR发生率为26.93％(28例)；ADR表现以皮肤及附件损害(67例,占64.42％)最为常见.结论 应慎用静脉用药,合理使用抗微生物药和辨证使用中药针剂以减少药品不良反应的发生.%Objective To provide reference for rational, safe uses of medications by analyzing the regularity and characteristics of adverse drug reactions ( ADR ) occurring in our clinic injection center.Methods 104 cases of ADRs occurring at our clinic injection center in 2011 were analyzed statistically.Results ADRs occurred mainly in the patients aged 19 to 40 ( 63 patients or 60.58％ ).Intravenous drip caused ADRs more easily than any other routes of administration ( 101 patients or 97.12％ ).The majority of ADRs were caused by uses of antimicrobial agents ( 70 patients or 67.31％ ).Quinolones were the leading antimicrobials of causing ADRs ( 28 patients or 40％ ).Injections of Chinese traditional medicine induced ADRs in 28 patients ( 26.93％ ).The most common presentations of ADRs were damageof skin and its appendages ( 67 patients or 64.42％ ).Conclusions Intravenous medications should be used with caution.Rational uses of antimicrobial drugs and uses of injections of Chinese traditional medicine based on syndrome differentiation can reduce the incidence of ADRs.
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