Objective To evaluate the functional state of specific somesthetic pathway and nerve, and to explore the changes of the somatosensory evoked potential (SEP) and sensory condution velocity(SCV)of type 2 disbetics and its relevantfactors. Methods PTNSEP and the sural nerve SCV were measured in 71 cases with type-2 diabetes melltus (DMgroup) and in 60's of control group, the numerical values of SEP and SCV were recorded and analyzed by SPSS10.0. Rusults (1)Compared with the control group, the N9 and N40 peak latencies of SEP were distinct prolong(P<0.01),SCV were distinct slower(P<0.01). (2)There was no signifincant difference in the two check. (3)the peak latencies of N9 and PN40 and SCV show a signifincant correlation with the fructose amine and the duration of disease,Conclusion To check SEPandSCV as soon as possible for the type-2 diabetics with lose control of the blood glucose level and long duration of disease. It was benefit to forepeart diagnoses and treatment of NS.%目的 了解糖尿病患者躯体感觉通路及周围神经受损程度,分析SEP、SCV的改变及其与临床参量的关系.方法 对71例糖尿病患者及60例健康人进行下肢体感诱发电位及腓肠神经感觉传导速度的测定.应用SPSS10.0统计软件分析糖尿病组的SEP及SCV的结果及其与临床相关因素(果糖胺、年龄、病程)的关系.结果 (1)糖尿病人各波峰潜伏期较正常人明显延长(P＜0.01), 感觉传导速度亦明显减慢(P＜0.01).(2)两种检查的异常率比较无显著性差异.(3)SEP的PF、P40潜伏期与果糖胺、病程呈正相关,感觉传导速度与果糖胺、病程呈负相关.结论 对血糖控制不好、病程长的DM患者即使无明确的神经系统症状和体征,也应尽早进行SEP、SCV常规检查,以利于神经系统并发症的早期诊断及治疗.
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