[目的]研究运用超高效液相色谱－三重四极杆串联质谱仪测定植物样品中全氟辛烷磺酸（PFOS）和全氟辛酸（PFOA）的可行性。[方法]建立了一种SPE 净化，超高效液相色谱－三重四极杆串联质谱仪 UPLC／MS／MS方法测定植物（绿萝）根、茎和叶中 PFOS和PFOA残留量，并优化了质谱条件和前处理方式，保留时间分别为2．26和2．17 min。[结果]采用碳酸钠（Na2CO3）、四丁基硫酸氢铵（TBAHS）、甲基叔丁基醚（MTBE）作为提取试剂，HLB小柱净化后PFOS在绿萝根、茎、叶中的加标回收率为46．53％～77．35％，变异系数为5．63％～18．52％；PFOA在绿萝根、茎、叶中的加标回收率为59．01％～100．46％，变异系数为2．85％～30．06％，检出限分别为26．90×10－4和3．09×10－4 ng，相关系数均大于0．998。[结论]超高效液相色谱－三重四极杆串联质谱仪测定植物样品中 PFOS 和PFOA满足化合物残留分析要求。%Objective] The study aimed to researched the residue analysis method of PFOS and PFOA using HPLC-MS/MS in plant samples. [ Method] PFOS and PFOA residue analysis method by SPE -ultra performance liquid chromatography tandem mass spectrometry ( UPLC/MS/MS) of in Epipremnum aureum was established.Analysis and determination conditions were optimized, the retention time of PFOS and PFOA is 2.26, 2.17 min.[Result] The experimental results showed that recoveries of PFOS and PFOA were in the range of 46.53%-77.35% and 59.01%-100.46% respectively.The coefficients of variation were 5.63%-18.52% and 2.85%-30.06% respectively.Minimum detect-able mass fraction of PFOS and PFOA were 26.90 ×10 -4 ng and 3.09 ×10 -4 ng,correlation coefficient is greater than 0.998.[Conclusion] Results showed that the developed method can be applied to analyze PFOS and PFOA in Epipremnum aureum.
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