According to the teaching situation of BengBu Medical College C language programming , it is more content and less class hour.Students’ learning enthusiasm is not high, resulting in poor teaching effect.The paper proposes mixed mode teaching reform based online teaching and flipped classroom.Online teaching resource is constructed, including syllabus, courseware and exercises etc.In order to facilitate students learning, the key knowledge points recorded micro video.Using flipped classroom teaching model, a new teaching model come into being where learning before class, class flipped and curing after class. Practice shows students are more recognized a series of measures of teaching reform .Learning enthusiasm has been improved large-ly, leading to a better teaching effect.%针对蚌埠医学院C语言程序设计教学普遍存在课时少、内容多、学生学习积极性不高、教学效果较差等问题，提出了线上教学与翻转课堂相结合的混合教学模式。课前学习构建了在线教学资源，包括教学大纲、课件、习题等，录制了关键知识点的微视频；课堂教学采用翻转课堂模式，形成了课前学习、课上翻转、课后强化的教学模式。实践表明，学生比较认可混合教学模式的一系列措施，学习积极性有了较大提高，教学效果较好。
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