Objective:To investigate the risk factors of acute exacerbation of chronic obstructive pulmonary disease ( AECOPD) patients complicated with ventilator-associated pneumonia ( VAP ) , and provide the basis for the clinical treatment of patients with AECOPD. Methods:The clinical data about the relationships of the occurrence of VAP and the general information ( age,gender and body mass index ) , nutrition support route ( enteral nutrition or total parenteral nutrition support ) , whether application of acid suppressive drugs,whether complicated with basic diseases, mechanical ventilation time in the 104 AECOPD patients were analyzed retrospectively. Results:The incidence of VAP was increased by total parenteral nutrition and combined with basic diseases( P0. 05). The results of logistic regression analysis were shown that the total parenteral nutrition support and combination with basic diseases were the independent risk factors for VAP (P 0.05).logistic回归分析结果表明,全静脉营养支持及合并基础疾病是影响VAP发生的独立危险因素(P<0.05).结论:AECOPD患者发生VAP的影响因素较多,应积极治疗基础疾病,早期肠内营养支持,改善患者的预后.
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