Basing on the modern medicine pathogens of the disease and combining the basic theory of traditional Chinese medicine,Professor HAN Mingxiang puts forward the fundament of perimenopausal syndrome is kidney yin de-ficiency and the key is stagnation of liver qi. Meanwhile he uses the decoction of Yiguan Jian and Xiaoyao San,addi-tion and subtraction Chinese herb with the changes of symptoms,in which are important beneficiaries of clinical cura-tive effect.%韩明向教授依据围绝经期综合征的现代医学发病机制，并结合中医基础理论，提出肾阴亏虚为该病的发病基础，肝失疏泄为该病的发病关键。临床运用一贯煎合逍遥散，并针对躯体不适主诉辅以对症用药，随证加减，既补肝体、又助肝用，寓疏于补，使滋补不壅滞，疏散不伤正，令阴血复、肝气疏。
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