Diabetes mellitus (DM) is one of the most important chronic diseases currently threatening human health worldwide.However,Diabetic kidney disease (DKD) is one of the main microvascular complications of DM;Vitamin D is a steroid hormone that is expressed in bone,kidney,intestines and other tissues.Vitamin D not only plays an important role in regulating calcium and phosphorus metabolism,but also involves the multiple biological effects of immune regulation,inflammatory response,cell proliferation and differentiation.In this paper,the effects of vitamin D on DKD and its research progress are discussed.%糖尿病(DM)是目前威胁全球人类健康的最重要慢性疾病之一;而糖尿病肾病(DKD)又是DM最主要的微血管并发症之一;维生素D是一种在骨、肾脏、肠道等组织器官均有表达的类固醇激素.不仅对调节钙磷代谢发挥着重要作用,同时还涉及免疫调节、炎症反应、细胞增殖及分化等多重生物学效应.本文将阐述维生素D对DKD的相关影响及其研究进展.
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