目的：探讨降钙素原（PCT）、C反应蛋白（CRP）正常的婴幼儿细菌性肺炎的临床特点。方法比较2013年1月1日至2015年3月30日期间，92例PCT、CRP正常（病例组）与95例PCT、CRP明显升高（对照组）的婴幼儿细菌性肺炎患儿的临床资料。结果病例组的月龄中位数为9.25个月，低于对照组的16.55个月，院前病程中位数为5.17 d，长于对照组的3.50 d；差异均有统计学意义（P<0.05）。病例组患儿发热、呼吸增快、低氧血症比例明显少于对照组，差异有统计学意义（P<0.05）。83.69%的病例组患儿院外使用抗生素，明显高于对照组，差异有统计学意义（P<0.05）。病例组的病原菌以流感嗜血杆菌最多，对照组则以肺炎链球菌最为常见。结论婴幼儿肺炎患儿PCT、CRP均正常仍不能排除细菌性肺炎的可能。%Objective To study clinical characteristics of bacterial pneumonia with normal procalcitonin (PCT) and C-reactive protein (CRP) in infants and toddlers. Methods Retrospective analysis of clinical data of infants and toddlers with bacterial pneumonia was performed from January 1, 2013 to March 30, 2015. Of them, there were 92 cases with normal PCT and CRP (case groupe) and 95 cases with signiifcantly higher PCT and CRP (control group). Results The median age was 9.25 months in the case group, which was signiifcantly younger than that in the control group (16.55 months) (P<0.05). The median of the course before admission was 5.17 days in the case group, which was signiifcantly longer than that in the control group (3.5 days) (P<0.05). The proportions of fever, dyspnea, and hypoxemia were signiifcantly lower in the case group than those in the control group (P<0.05). Administration of antibiotics before admission was found in 83.69%of cases in the cases group, which was higher than that in the control group (P<0.05). The most common pathogens in the case group was Haemophilus inlfuenza, while Streptococcus pneumonia was the most common in the control group. Conclusion The possibility of bacterial infection cannot be ruled out in pneumonia with normal CRP and PCT in infants and toddlers.
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