目的 应用剪切波弹性成像技术检测颈动脉粥样斑块的弹性模量,评估脑梗死患者斑块的易损性.方法 选取我院急性脑梗死患者60例(脑梗死组)和91例非脑梗死患者(对照组),应用剪切波弹性成像测量两组颈动脉斑块的杨氏模量值[平均值(Emean)、最小值(Emin)、最大值(Emax)及标准差(Sd)],并对其进行比较分析.结果 脑梗死组颈动脉斑块Emean、Emin分别为(18.17±15.29)kPa、(10.36±8.73)kPa,均低于对照组[(27.11±17.10)kPa、(15.86±15.60)kPa],差异均有统计学意义(均P<0.05).结论 剪切波弹性成像技术可通过检测颈动脉斑块的杨氏模量平均值和最小值评估斑块的易损性,或可作为预测脑梗死发生的风险参数.%Objective To measure the Young's modulus of carotid atherosclerotic plaque by shear wave elastography (SWE) and to assess the vulnerability of plaque in patients with acute cerebral infarction. Methods Sixty patients with acute cerebral infarction as cerebral infarction group and 91 patients with non-cerebral infarction as control group were selected,the Young's modulus of carotid atherosclerotic plaque[the mean value(Emean),the minimum value(Emin),the maximum value (Emax), and the standard deviation(Sd)] were measured by SWE . Then the difference of plaques ' Young ' s modulus between the cerebral infarction group and control group were compared. Results The Emean and Emin of carotid atherosclerotic plaque in cerebral infarction group were (18.17±15.29) kPa and (10.36±8.73)kPa,respectively,which were lower than those in control group[(27.11 ±17.10)kPa and(15.86 ±15.60)kPa],there were significant difference(all P<0.05). Conclusion Using SWE to detect carotid plaques' Emean and Emin of Young's modulus can assess the vulnerability of plaque,and it may be used as parameters for predicting the risk of cerebral infarction.
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