Objective: To investigate the effect of aerobic exercise training combined with routine medication on the red blood cell parameters, vascular endothelial function and cardiac function in elderly patients with coronary heart disease complicated with chronic heart failure.Methods: A total of 110 elderly patients with coronary heart disease and chronic heart failure were divided into control group (n=54) and observation group (n=56) according to random data table.The patients in control group were treated with routine medicine, and the patients in the observation group received routine medicine combined with aerobic exercise training.The levels of the red blood cell parameters, vascular endothelial function and cardiac function indexes before and after treatment were compared between the two groups.Results: Before treatment, there was no significant difference in HCT, RDW, RBC, NO, ET-1, LVEF, LVEDD and LVESD levels between the two groups (P>0.05).After treatment, the differences in HCT and RBC levels between two groups were not statistically significant (P>0.05);The levels of RDW, ET-1, LVEDD and LVESD in the observation group after treatment were significantly lower than that before treatment, and significantly lower than that of the control group after treatment (P<0.05);The levels of NO and LVEF in the two groups after treatment were significantly higher than that before treatment (P<0.05), and the levels of NO and LVEF in the observation group were significantly higher than that of the control group after treatment (P<0.05).Conclusion: The clinical effect of aerobic exercise training combined with routine medication in the treatment of senile coronary heart disease accompanied by chronic heart failure was significant, which can effectively improve vascular endothelial function and heart function, and increase the RDW level of patients, it has important clinical value.%目的:探讨有氧运动训练联合常规药物治疗老年冠心病伴慢性心力衰竭,对患者红细胞参数、血管内皮功能及心功能的影响.方法:110例老年冠心病伴慢性心力衰竭患者依据随机数据表法分为对照组(n=54)和观察组(n=56).对照组给予常规药物治疗,观察组患者给予常规药物联合有氧运动训练治疗,比较治疗前后两组的红细胞参数、血管内皮功能及心功能指标水平.结果:治疗前,观察组的HCT、RDW、RBC、NO、ET-1、LVEF、LVEDD及LVESD水平与对照组比较,差异无显著性(P>0.05).治疗后,两组HCT和RBC水平比较,差异无统计学意义(P>0.05);观察组RDW、ET-1、LVEDD及LVESD水平均显著低于组内治疗前,均显著低于对照组治疗后水平,差异比较均有显著性(P<0.05);两组治疗后NO和LVEF水平较组内治疗前均显著升高(P<0.05),且治疗后观察组NO和LVEF水平显著高于对照组,差异有统计学意义(P<0.05).结论:有氧运动联合常规药物治疗老年冠心病伴慢性心力衰竭效果显著,可有效改善患者血管内皮功能及心功能,提升RDW水平,具有重要的临床价值.
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