ZnO nanoparticles (NPs) have been widely concerned and studied due to their unique physicochemical and biological characteristics.As a new type of multi-functional material,ZnO NPs have antibacterial,osteogenic and anticancer functions.In recent years,ZnO NPs have been added to the dental materials,such as mouthwash,dental filling materials and titanium implants,which improve the comprehensive performance of dental materials.This paper summarizes and analyzes the previous research findings to explore the antibacterial mechanism of ZnO NPs and their application and biosafety in oral treatment.%纳米氧化锌因其独特的理化和生物学特性,一直被广泛关注和研究.作为一种新型多功能材料,纳米氧化锌不仅具有良好的抗菌性能,而且兼顾成骨和抗癌功能.近年来研究者们将纳米氧化锌添加到漱口水、口腔充填材料、钛种植体等口腔材料中,进一步提高了牙科材料的综合性能.本文对现有相关研究成果进行了总结、归纳和分析,深入探讨纳米氧化锌的抗菌机制,进一步对纳米氧化锌在口腔治疗中的应用及生物安全性研究等方面进行阐述.
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