目的：探讨粗针穿刺活检对乳腺癌患者术后5年生存率的影响。方法选取2004-2005年期间行手术切除，且依照个体病情完成了全部治疗方案，随访时间＞5年的乳腺癌患者134例。其中，67例术前进行粗针穿刺活检和新辅助化疗（观察组），67例同期采用术中快速冰冻病理诊断者为对照组，对2组术后5年生存率进行比较。结果观察组和对照组术后5年生存率分别为78．46％、76．56％，2组比较差异无统计学意义（P＞0．05）。结论粗针穿刺活检和新辅助化疗对乳腺癌术后5年生存率无不良影响。%Objective To investigate the impact of coarse needle biopsy on the 5-year survival rate in patients undergoing surgery for breast cancer.Methods A total of 134 patients who re-ceived surgery for breast cancer and underwent all treatments between 2004 and 2005 were fol-lowed up for more than 5 years.Among the 134 patients,67 received coarse needle biopsy and neoadjuvant chemotherapy before operation(observation group),and 67 received rapid intraopera-tive frozen section diagnosis(control group).The 5-year survival rate was compared between the two groups.Results The 5-year survival rate was 78.46% in observation and 76.56% in control group.There was no significant difference between the two groups(P>0.05).Conclusion Coarse needle biopsy and neoadj uvant chemotherapy do not affect the 5-year survival rate in patients un-dergoing surgery for breast cancer.
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