目的 观察低分子肝素钙联合银杏达莫治疗急性心源性脑栓塞患者的临床疗效.方法 选取解放军第八五院神经内科2015年7月至2016年7月收治的急性心源性脑栓塞患者80例,经患者知情和家属同意,采用平均分组的方式将80例患者分为观察组和对照组,每组40例,2组患者在入院之后均给予相同的基础治疗和预防并发症治疗,观察组采用低分子肝素钙联合银杏达莫治疗,对照组仅给予低分子肝素钙治疗.比较2组患者治疗前后的神经功能缺损恢复情况及临床疗效,同时观察2组患者不良反应发生情况.结果 治疗后观察组患者的神经功能缺损评分明显高于对照组,差异有统计学意义(P<0.05);观察组患者总有效率为97.5%,明显高于对照组患者的67.5%,差异有统计学意义(P<0.05);2组患者不良反应发生率比较差异无统计学意义(P>0.05).结论 低分子肝素钙联合银杏达莫治疗急性心源性脑栓塞较单用低分子肝素钙效果更明显.%Objective To investigate the clinical efficacy of low molecular weight heparin combined with ginkgo dipyridamole on the patients with acute cardiogenic cerebral embolism .Methods Eighty cases of cardiogenic cerebral embolism admitted into the Department of Neurology of the hospital from July 2015 to July 2016 were recruited as research subjects .With the knowledge of the pa-tients and consent of their dependents , the patients were equally divided into 2 groups: the observation group and the control group , each consisting of 40 patients.After admission into the hospital , the patients of the 2 groups were given the same basic treatment and the treatment for complication prevention .The patients of the observation group received treatment of low molecular weight heparin com -bined with ginkgo dipyridamole for the treatment of acute cardiogenic cerebral embolism , while the patients of the control group were just given low molecular weight heparin .Recovery of neurological insufficiency and clinical efficacy were compared between the 2 groups both before and after treatment , and at the same time, adverse reactions were also observed and compared between the 2 groups.Results After treatment, the neurological function scores of the observation group were significantly higher than those of the control group , and statistical significance could be seen when comparisons were made between them (P<0.05).Total therapeutic efficacy of the observa-tion group was 97.5%, which was significantly higher than that of the control group (67.5%), also with statistical significance (P<0.05).There was no statistical significance in adverse reactions , when comparisons were made between the 2 groups(P>0.05). Conclusion Low molecular weight heparin combined with ginkgo dipyridamole in the treatment of acute cardiogenic cerebral embolism could produce much better effect than single application of low molecular weight heparin .
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