目的:探讨经皮肝胆管穿刺引流术(PTCD)加胆道支架置入术治疗恶性梗阻性黄疸(MOJ)的临床应用价值.方法:分析130例行PTCD加胆道支架置入术的MOJ患者的临床资料,进行临床观察.结果:手术技术成功率达97.7%;术后肝功能较术前明显改善(P<0.05);术后并发症有胆道感染、急性胰腺炎及支架脱落等,经治疗后均好转;17例患者因肿瘤进展及多脏器功能衰竭死亡,中位生存期8.7个月.结论:PTCD 加胆道支架置入术治疗MOJ安全有效,但术后需注意并发症的预防与治疗.%Objective:To explore the clinical application value of percutaneous transhepatic catheterizde drainage (PTCD) combined with expandable metallic biliary endoprosthesis in the treatment of malignant obstructive jaundice (MOJ).Methods:The clinical data of 130 patients with MOJ who received PTCD combined with expandable metallic biliary endoprosthesis were analyzed for clinical observation.Results:The surgical successful rate was up to 97.7%,which improved significantly than operation before (P<0.05).The postoperative complications include bilary tract infection,acute pancreatitis and stent detachment,which were improved after symptomatic treatment.A total of 17 patients died of tumor progression and multi-organ failure,with median survival time being 8.7 months.Conclusion:PTCD combined with expandable metallic biliary endoprosthesis is safe in the treatment of MOJ,but the prevention and treatment of postoperative complications should be highly concerned.
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