Objective To understand the knowledge, attitude and practice (KAP) of hospice care of nurses in tumor hospitals and the influence factors of KAP and to provide reference for the implementation of hospice care in tumor hospitals. Methods A total of 408 nurses were investigated with the questionnaire of hospice care KAP of nurses. Results The score of KAP and standard score were (14.03±3.31) and 70.15, (3.50±0.27) and 69.95, (4.11±0.73) and 82.17 respectively. Nurses only presented good practice of hospice care. Income, educational background, gender, with special training of hospice care or not, obtaining knowledge of hospice care from other medical staff or not and practice score were influence factors of hospice care knowledge (R2=0.279,F=12.767,P=0.000). Whether obtaining hospice care knowledge through medias such as TV and the internet and practice score exerted influence on the attitude of hospice care (R2=0.147,F=9.863,P=0.000). Family formation, the score of knowledge and attitude were influence factors of hospice care practice (R2=0.120,F=18.513,P=0.000). Conclusion There is separation among knowledge, attitude and practice of hospice care. It is necessary to improve hospice care knowledge, promote the shift of attitude and standardize the practice of nurses in tumor hospitals.%目的：了解长沙市肿瘤专科医院护士临终关怀知信行现状及影响因素，为长沙市肿瘤专科医院开展临终关怀服务提供理论依据。方法通过护士临终关怀知信行问卷，对长沙市2所肿瘤专科医院的408名护士进行调查。结果肿瘤专科医院护士临终关怀知识、态度、行为得分及标准分分别是（14.03±3.31）分、70.15分，处于及格水平；（3.50±0.27）分、69.95分，处于及格水平；（4.11±0.73）分、82.17分，处于良好水平。月收入、学历、性别、是否通过专门培训学习临终知识、是否通过其他医护人员学习临终知识、行为得分对临终知识有影响（R2=0.279，F=12.767，P=0.000）；是否通过专门培训学习临终知识、是否通过电视、网络等媒体学习临终知识、行为得分对临终态度有影响（R2=0.147，F=9.863，P=0.000）；家庭形态、知识得分、态度得分对临终行为有影响（R2=0.120，F=18.513，P=0.000）。结论肿瘤专科医院护士临终关怀知信行存在知信分离、知行分离、信行分离现象，因此肿瘤专科医院应进一步提高护士临终关怀知识水平，促进临终关怀态度转变，规范临终关怀行为。
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