Objective To investigate the normal value and its regularity of long-axis systolic function of left ventricle in healthy subjects. Methods Two-demensional dynamic images of left ventricle in 100 healthy subjects were collected, and peak systolic strain (PSS), peak longitudianl displacement (PLD) and time to peak logitudinal strain (TPLS) of each segment of left ventricular were measured and analyzed. Results The normal values of the parameters of left ventricle were: PSS (-24.46 ± 4.98)%, PLD (12.09 ± 6.26)mm, TPLS (362.57 ± 40.92)ms. From cardiac base to cardiac apex, PSS was gradually increased while PLD and TPLS were gradually decreased (P < 0.01). PSS and TPLS, as well as PLD and TPLS were negatively correlated (r = -0.548, r = -0.211, P < 0.01), while PLD and TPLS were positively correlated (r = 0.233, P < 0.01). The maximum difference of TPLS of the corresponding ventricular wall of left ventricle was 125 ms, while the standard deviation of the difference was 31.77 ms. Conclusion Both part and whole systolic function of left ventricular can be evaluated by PSS, PLD and TPLS directly and quantitatively.%目的:探讨正常人左室心肌纵向应变各参数的正常值及其变化规律.方法:采集100例正常人左心室纵向二维动态图像,测量左室壁各节段纵向收缩峰值应变(Peak Systolic Strain,PSS)、纵向峰值位移(Peak Longitudinal Displacement,PLD)及纵向应变达峰时间(Time to Peak Longitudinal Strain,TPLS),对比分析各参数测值.结果:(1)左室整体各参数的正常值:PSS(-24.46±4.98)％、PLD(12.09±6.26)mm、TPLS(362.57±40.92)ms.(2)左室三段间各参数变化规律:PSS自基底段向心尖段逐渐增高,而PLD、TPLS逐渐减低,三段间参数差异均有统计学意义(P＜0.01).(3)各参数相关性:PSS和PLD、PSS和TPLS呈负相关(r=-0.548;r=-0.211,P＜0.01)；PLD和TPLS呈正相关(r=0.233,P＜ 0.01).(4)左室同步性分析:左室三段相对应室壁最大差值(TPLS-dif)及差值标准差(TPLS-dif-SD)为125ms、31.77ms.结论:PSS、PLD和TPLS可直观、定量地评价左心室局部和整体收缩功能.
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